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Calcipotriol Monohydrate

Calcipotriol Monohydrate
Calcipotriol Monohydrate
Product Code : 03
Product Description
Product Details:

Packaging Size 25 kg

Calcipotriol (hydrate) is a low-calcemic vitamin D receptor (VDR) agonist. Calcipotriol (hydrate) is about 200 times less potent in its effects on calcium metabolism than vitamin D (1,25[OH]D3).Binding of calcipotriol (hydrate) to the VDR increases AP-1, a transcription factor important for keratinocyte differentiation, and reduces expression of JunB protein, a transcriptional activator in the inflammatory response.Calcipotriol (hydrate) also induces expression of thymic stromal lymphopoietin, which triggers T-cell differentiation in keratinocytes.

Specification:

  • Formal Name: 24-cyclopropyl-(1α,3β,5Z,7E,22E,24S)-9,10-secochola-5,7,10(19),22-tetraene-1,3,24-triol, monohydrate
  • CAS Number :112828-00-9
  • Synonyms : Calcipotriene
  • Molecular Formula : C27H40O3 · H2O
  • Formula Weight :412.6
  • Purity: ≥98%
  • Formulation A crystalline solid
  • Product Type: API
Product Details:

Packaging Size 25 kg

Calcipotriol (hydrate) is a low-calcemic vitamin D receptor (VDR) agonist. Calcipotriol (hydrate) is about 200 times less potent in its effects on calcium metabolism than vitamin D (1,25[OH]D3).Binding of calcipotriol (hydrate) to the VDR increases AP-1, a transcription factor important for keratinocyte differentiation, and reduces expression of JunB protein, a transcriptional activator in the inflammatory response.Calcipotriol (hydrate) also induces expression of thymic stromal lymphopoietin, which triggers T-cell differentiation in keratinocytes.

Specification:

  • Formal Name: 24-cyclopropyl-(1α,3β,5Z,7E,22E,24S)-9,10-secochola-5,7,10(19),22-tetraene-1,3,24-triol, monohydrate
  • CAS Number :112828-00-9
  • Synonyms : Calcipotriene
  • Molecular Formula : C27H40O3 · H2O
  • Formula Weight :412.6
  • Purity: ≥98%
  • Formulation A crystalline solid
  • Product Type: API
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