Olmesartan is an angiotensin II receptor antagonist used to treat high blood pressure. They work by reducing the levels of prostaglandins, which are chemicals that are responsible for pain and the fever and tenderness that occur with inflammation. Olmesartan blocks the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower concentrations of prostaglandins. As a consequence, inflammation, pain and fever are reduced.
It is indicated for the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents. The olmesartan molecule includes one tetrazole group (a five-member heterocyclic ring of four nitrogen atoms and one carbon atom) and one imidazole group (a five-membered planar heterocyclic aromatic ring of two nitrogen and three carbon atoms, classified as an alkaloid).
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